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antiandrogens in women
Gynakologe. 1980;13:1-17.
Clinical use of antiandrogens in the female
Moltz L, Schwartz U, Hammerstein J.
PIP: The use of antiandrogens (principally cyproterone acetate CPA) to treat women with symptoms of hypersecretion of androgens such as hair loss is discussed. ..snip... Seborrhea and endogenous acne can be effectively treated with all types of antiandrogen preparations. Androgenetic alopecia (pattern hair loss) can also be treated in a majority of cases with CPA preparations. CPA treatment should not last longer than 12 months. High dosage CPA use by ovulating women causes suppression of the preovulatory LH and FSH peaks but has little effect on basal levels; in postmenopausal women, the basal LH and FSH levels are significantly reduced. Use of CPA by itself causes a significant decrease in the levels of testosterone and delta-4-andostendion 3,17-dion. Use of CPA/EE combinations causes an increase in SHBG and the blood cortisol levels. Protein metabolism, hematopoesis, blood coagulation, and liver function are not affected by CPA use. Reduced glucose utilization and an increase in triglyceride levels are observed during CPA use. snip....
Edited for hair loss blog